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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Repaglinide | |
| Synonyms |
REPAGLINIDE Benzoic Acid, 2-ethoxy-4-(2-((3-methyl-1-(2-(1-piperidinyl)phenyl)butyl)amino)-2-oxoethyl)-,(S)- AG-EE 623 ZW Repaglinide (+)-2-Ethoxy-alpha-(((S)-alpha-isobutyl-o-piperidinobenzyl)carbamoyl)-p-toluic Acid Prandin |
|
| Definitions |
A nonsulfonylurea insulin secretagogue belonging to the melgitinide class with hypoglycemic activity. Repaglinide is rapidly absorbed and has a rapid onset and short duration of action. This agent is metabolized in the liver by CYP2C8 and CYP3A4 and its metabolites are excreted in the bile. Repaglinide has a half-life of one hour. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47703 |
|
| CAS_Registry |
135062-02-1
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|
| Chemical_Formula |
C27H36N2O4
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|
| code |
C47703
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
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| Contributing_Source |
CTRP FDA
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|
| DEFINITION |
A nonsulfonylurea insulin secretagogue belonging to the melgitinide class with hypoglycemic activity. Repaglinide is rapidly absorbed and has a rapid onset and short duration of action. This agent is metabolized in the liver by CYP2C8 and CYP3A4 and its metabolites are excreted in the bile. Repaglinide has a half-life of one hour.
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|
| Display_Name |
Repaglinide
|
|
| FDA_UNII_Code |
668Z8C33LU
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|
| FULL_SYN |
REPAGLINIDE Benzoic Acid, 2-ethoxy-4-(2-((3-methyl-1-(2-(1-piperidinyl)phenyl)butyl)amino)-2-oxoethyl)-,(S)- AG-EE 623 ZW Repaglinide (+)-2-Ethoxy-alpha-(((S)-alpha-isobutyl-o-piperidinobenzyl)carbamoyl)-p-toluic Acid Prandin
|
|
| label |
Repaglinide
|
|
| Legacy Concept Name |
Repaglinide
|
|
| NCI_Drug_Dictionary_ID |
775334
|
|
| PDQ_Closed_Trial_Search_ID |
775334
|
|
| PDQ_Open_Trial_Search_ID |
775334
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|
| Preferred_Name |
Repaglinide
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|
| prefixIRI |
Thesaurus:C47703
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|
| Semantic_Type |
Pharmacologic Substance
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|
| UMLS_CUI |
C0246689
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|
| subClassOf |
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