National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Propylhexedrine

Synonyms

Propylhexedrine

Hydromethamphetamine

PROPYLHEXEDRINE

1-Cyclohexyl-2-(methylamino)propane

(+-)-N,alpha-Dimethylcyclohexaneethylamine

Dristan

Definitions

A propylamine derivative with sympathomimetic property. Propylhexedrine binds to and activates alpha-adrenergic receptors in the mucosa of the respiratory tract, thereby mimicking the actions of norepinephrine and epinephrine. This results in vasoconstriction and reduces swelling and inflammation of the mucous membrane lining, therefore relieving nasal and sinus congestion.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47694

CAS_Registry

101-40-6

Chemical_Formula

C10H21N

code

C47694

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A propylamine derivative with sympathomimetic property. Propylhexedrine binds to and activates alpha-adrenergic receptors in the mucosa of the respiratory tract, thereby mimicking the actions of norepinephrine and epinephrine. This results in vasoconstriction and reduces swelling and inflammation of the mucous membrane lining, therefore relieving nasal and sinus congestion.

FDA_UNII_Code

LQU92IU8LL

FULL_SYN

Propylhexedrine

Hydromethamphetamine

PROPYLHEXEDRINE

1-Cyclohexyl-2-(methylamino)propane

(+-)-N,alpha-Dimethylcyclohexaneethylamine

Dristan

label

Propylhexedrine

Legacy Concept Name

Propylhexedrine

NSC Number

32410

Preferred_Name

Propylhexedrine

prefixIRI

Thesaurus:C47694

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0033508

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29709

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