loading...| Preferred Name | Promazine Hydrochloride | |
| Synonyms |
PROMAZINE HYDROCHLORIDE 10-(3-(Dimethylamino)propyl)phenothiazine Monohydrochloride Promazine Hydrochloride 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, Monohydrochloride Sparine Starazin Talofen |
|
| Definitions |
The hydrochloride salt form of promazine, a phenothiazine derivative with antipsychotic and antiemetic properties. Promazine hydrochloride blocks postsynaptic dopamine receptors D1 and D2 in the mesolimbic and medullary chemoreceptor trigger zone (CTZ), thereby decreasing stimulation of the vomiting center in the brain and psychotic effects, such as hallucinations and delusions. In addition, this agent blocks alpha-adrenergic receptors and exhibits strong anticholinergic activity. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47691 |
|
| CAS_Registry |
53-60-1 |
|
| CHEBI_ID |
CHEBI:8460 |
|
| Chemical_Formula |
C17H20N2S.HCl |
|
| code |
C47691 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The hydrochloride salt form of promazine, a phenothiazine derivative with antipsychotic and antiemetic properties. Promazine hydrochloride blocks postsynaptic dopamine receptors D1 and D2 in the mesolimbic and medullary chemoreceptor trigger zone (CTZ), thereby decreasing stimulation of the vomiting center in the brain and psychotic effects, such as hallucinations and delusions. In addition, this agent blocks alpha-adrenergic receptors and exhibits strong anticholinergic activity. |
|
| FDA_UNII_Code |
U16EOR79U4 |
|
| FULL_SYN |
PROMAZINE HYDROCHLORIDE 10-(3-(Dimethylamino)propyl)phenothiazine Monohydrochloride Promazine Hydrochloride 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, Monohydrochloride Sparine Starazin Talofen |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Promazine Hydrochloride |
|
| Legacy Concept Name |
Promazine_Hydrochloride |
|
| NSC Number |
17468 |
|
| Preferred_Name |
Promazine Hydrochloride |
|
| prefixIRI |
Thesaurus:C47691 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0546875 |
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| subClassOf |