Preferred Name |
Procaine Hydrochloride |
|
Synonyms |
Gerovital H3 Benzoic Acid, 4-amino-, 2-(diethylamino)ethyl Ester, Monohydrochloride Procaine Hydrochloride PROCAINE HYDROCHLORIDE 2-(Diethylamino)ethyl p-aminobenzoate Monohydrochloride Allocaine Novocain |
|
Definitions |
The hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47688 |
|
CAS_Registry |
51-05-8 |
|
Chemical_Formula |
C13H20N2O2.HCl |
|
code |
C47688 |
|
Concept_In_Subset | ||
Contributing_Source |
FDA |
|
DEFINITION |
The hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation. |
|
FDA_UNII_Code |
95URV01IDQ |
|
FULL_SYN |
Gerovital H3 Benzoic Acid, 4-amino-, 2-(diethylamino)ethyl Ester, Monohydrochloride Procaine Hydrochloride PROCAINE HYDROCHLORIDE 2-(Diethylamino)ethyl p-aminobenzoate Monohydrochloride Allocaine Novocain |
|
Has_Free_Acid_Or_Base_Form | ||
label |
Procaine Hydrochloride |
|
Legacy Concept Name |
Procaine_Hydrochloride |
|
NSC Number |
169497 |
|
Preferred_Name |
Procaine Hydrochloride |
|
prefixIRI |
Thesaurus:C47688 |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0358490 |
|
subClassOf |