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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Pindolol | |
| Synonyms |
1-(1H-Indol-4-yloxy)-3-((1-methylethyl)amino)-2-propanol Carvisken PINDOLOL Pindolol Visken |
|
| Definitions |
An aryloxypropanolamine derivative with antihypertensive property. Pindolol competitively binds to beta-adrenergic receptors, resulting in a decrease in beta-adrenergic activities, i.e., vasodilation, and negative chronotropic and inotropic effects. In addition, this agent blocks serotonin (5-HT) 1A receptors, thereby increasing the available serotonin in the brain. Increased serotonin levels augment the antidepressant action of selective serotonin reuptake inhibitors and monoamine oxidase inhibitors. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47673 |
|
| CAS_Registry |
13523-86-9
|
|
| CHEBI_ID |
CHEBI:8214
|
|
| Chemical_Formula |
C14H20N2O2
|
|
| code |
C47673
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
An aryloxypropanolamine derivative with antihypertensive property. Pindolol competitively binds to beta-adrenergic receptors, resulting in a decrease in beta-adrenergic activities, i.e., vasodilation, and negative chronotropic and inotropic effects. In addition, this agent blocks serotonin (5-HT) 1A receptors, thereby increasing the available serotonin in the brain. Increased serotonin levels augment the antidepressant action of selective serotonin reuptake inhibitors and monoamine oxidase inhibitors.
|
|
| FDA_UNII_Code |
BJ4HF6IU1D
|
|
| FULL_SYN |
1-(1H-Indol-4-yloxy)-3-((1-methylethyl)amino)-2-propanol Carvisken PINDOLOL Pindolol Visken
|
|
| label |
Pindolol
|
|
| Legacy Concept Name |
Pindolol
|
|
| Preferred_Name |
Pindolol
|
|
| prefixIRI |
Thesaurus:C47673
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0031937
|
|
| subClassOf |
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