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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Oxytetracycline Hydrochloride | |
| Synonyms |
5-Hydroxytetracycline Hydrochloride OXYTETRACYCLINE HYDROCHLORIDE (4S,4aR,5S,5aR,6S,12aS)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide, Monohydrochloride Oxytetracycline Hydrochloride Oxy-Kesso-Tetra Alamycin Dalinmycin Terramycin |
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| Definitions |
The hydrochloride salt form of oxytetracycline, a tetracycline derivative produced by Streptomyces rimosus exhibiting antimicrobial activity. Oxytetracycline hydrochloride interferes with binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby preventing peptide elongation and inhibiting protein synthesis. It is often used to treat skin conditions. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47649 |
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| CAS_Registry |
2058-46-0
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| Chemical_Formula |
C22H24N2O9.HCl
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| code |
C47649
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| Concept_In_Subset | ||
| Contributing_Source |
FDA
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| DEFINITION |
The hydrochloride salt form of oxytetracycline, a tetracycline derivative produced by Streptomyces rimosus exhibiting antimicrobial activity. Oxytetracycline hydrochloride interferes with binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby preventing peptide elongation and inhibiting protein synthesis. It is often used to treat skin conditions.
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| FDA_UNII_Code |
4U7K4N52ZM
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| FULL_SYN |
5-Hydroxytetracycline Hydrochloride OXYTETRACYCLINE HYDROCHLORIDE (4S,4aR,5S,5aR,6S,12aS)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide, Monohydrochloride Oxytetracycline Hydrochloride Oxy-Kesso-Tetra Alamycin Dalinmycin Terramycin
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| Has_Free_Acid_Or_Base_Form | ||
| label |
Oxytetracycline Hydrochloride
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|
| Legacy Concept Name |
Oxytetracycline_Hydrochloride
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|
| NSC Number |
9169
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| Preferred_Name |
Oxytetracycline Hydrochloride
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| prefixIRI |
Thesaurus:C47649
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0017449
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| subClassOf |
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