loading...| Preferred Name |
Methylergonovine Maleate |
|
| Synonyms |
METHYLERGONOVINE MALEATE Methylergonovine Maleate Ergoline-8-carboxamide, 9,10-didehydro-N-((1S)-1-(hydroxymethyl)propyl)-6-methyl-,(8beta)-,(2Z)-2-butenedioate(1:1)(salt) Maleic Acid, Methyl Ergonovine Methergine |
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| Definitions |
The maleate salt of methylergonovine, a semi-synthetic ergot alkaloid with vasoconstrictive and uterotonic effects. Methylergonovine stimulates serotoninergic and dopaminergic receptors as well as inhibits the release of endothelial-derived relaxation factor. This results in arterial vasoconstriction and increased uterine smooth muscle contractions. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47618 |
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| CAS_Registry |
57432-61-8 7054-07-1 |
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| Chemical_Formula |
C20H25N3O2.C4H4O4 |
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| code |
C47618 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA |
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| DEFINITION |
The maleate salt of methylergonovine, a semi-synthetic ergot alkaloid with vasoconstrictive and uterotonic effects. Methylergonovine stimulates serotoninergic and dopaminergic receptors as well as inhibits the release of endothelial-derived relaxation factor. This results in arterial vasoconstriction and increased uterine smooth muscle contractions. |
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| FDA_UNII_Code |
IR84JPZ1RK |
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| FULL_SYN |
METHYLERGONOVINE MALEATE Methylergonovine Maleate Ergoline-8-carboxamide, 9,10-didehydro-N-((1S)-1-(hydroxymethyl)propyl)-6-methyl-,(8beta)-,(2Z)-2-butenedioate(1:1)(salt) Maleic Acid, Methyl Ergonovine Methergine |
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| Has_Free_Acid_Or_Base_Form | ||
| label |
Methylergonovine Maleate |
|
| Legacy Concept Name |
Methylergonovine_Maleate |
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| NSC Number |
186067 |
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| Preferred_Name |
Methylergonovine Maleate |
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| prefixIRI |
Thesaurus:C47618 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0733811 |
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| subClassOf |