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National Cancer Institute Thesaurus
| Preferred Name | Halcinonide | |
| Synonyms |
Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-,(11beta,16alpha)- 21-Chloro-9-fluoro-11beta,16alpha,17-trihydroxypregn-4-ene-3,20-dione Cyclic 16,17-Acetal with Acetone Halcinonide HALCINONIDE Halciderm Halcort Halog Volog |
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| Definitions |
A topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Halcinonide exerts its effect by interacting with specific intracellular receptors, and the ligand-receptor complex subsequently modulates gene expressions via the typical glucocorticoid signalling pathway. This results in the synthesis of certain anti-inflammatory proteins as well as in synthesis inhibition of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. (NCI05) |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47552 |
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| CAS_Registry |
3093-35-4
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| Chemical_Formula |
C24H32ClFO5
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|
| code |
C47552
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| Concept_In_Subset | ||
| Contributing_Source |
FDA
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|
| DEFINITION |
A topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Halcinonide exerts its effect by interacting with specific intracellular receptors, and the ligand-receptor complex subsequently modulates gene expressions via the typical glucocorticoid signalling pathway. This results in the synthesis of certain anti-inflammatory proteins as well as in synthesis inhibition of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. (NCI05)
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| FDA_UNII_Code |
SI86V6QNEG
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| FULL_SYN |
Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-,(11beta,16alpha)- 21-Chloro-9-fluoro-11beta,16alpha,17-trihydroxypregn-4-ene-3,20-dione Cyclic 16,17-Acetal with Acetone Halcinonide HALCINONIDE Halciderm Halcort Halog Volog
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|
| label |
Halcinonide
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| Legacy Concept Name |
Halcinonide
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|
| Preferred_Name |
Halcinonide
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| prefixIRI |
Thesaurus:C47552
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0733757
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| subClassOf |
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