Preferred Name | Flurandrenolide | |
Synonyms |
6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione, cyclic 16,17-acetal with Acetone Fludroxycortide FLURANDRENOLIDE Flurandrenolide Cordran |
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Definitions |
A synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Flurandrenolide exerts its effects by interacting with specific cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions. |
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ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47537 |
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CAS_Registry |
1524-88-5 |
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Chemical_Formula |
C24H33FO6 |
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code |
C47537 |
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Concept_In_Subset | ||
Contributing_Source |
FDA |
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DEFINITION |
A synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Flurandrenolide exerts its effects by interacting with specific cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions. |
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FDA_UNII_Code |
8EUL29XUQT |
|
FULL_SYN |
6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione, cyclic 16,17-acetal with Acetone Fludroxycortide FLURANDRENOLIDE Flurandrenolide Cordran |
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label |
Flurandrenolide |
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Legacy Concept Name |
Flurandrenolide |
|
Preferred_Name |
Flurandrenolide |
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prefixIRI |
Thesaurus:C47537 |
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Semantic_Type |
Pharmacologic Substance |
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UMLS_CUI |
C0016374 |
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subClassOf |