National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Etonogestrel
Synonyms

ETONOGESTREL

(17-alpha)-13-Ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one

Etonogestrel

3-Keto-Desogestrel

Implanon

Definitions

A synthetic form of the naturally occurring female sex hormone progesterone. Etonogestrel binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor mediated gene expression. As a result of the negative feedback mechanism, luteinizing hormone (LH) release is inhibited, which leads to an inhibition of ovulation and an alteration in the cervical mucus and endometrium.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47528

CAS_Registry

54048-10-1

CHEBI_ID

CHEBI:50777

Chemical_Formula

C22H28O2

code

C47528

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic form of the naturally occurring female sex hormone progesterone. Etonogestrel binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor mediated gene expression. As a result of the negative feedback mechanism, luteinizing hormone (LH) release is inhibited, which leads to an inhibition of ovulation and an alteration in the cervical mucus and endometrium.

FDA_UNII_Code

304GTH6RNH

FULL_SYN

ETONOGESTREL

(17-alpha)-13-Ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one

Etonogestrel

3-Keto-Desogestrel

Implanon

label

Etonogestrel

Legacy Concept Name

Etonogestrel

Preferred_Name

Etonogestrel

prefixIRI

Thesaurus:C47528

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0047683

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C776

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