loading...| Preferred Name |
Etodolac |
|
| Synonyms |
1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic Acid Etodolic Acid ETODOLAC Etodolac Lodine Ultradol |
|
| Definitions |
A pyranocarboxylic acid and non-steroidal anti-inflammatory drug (NSAID) with antipyretic and analgesic activities. Etodolac inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, and inflammation. It also inhibits platelet aggregation by blocking platelet cyclooxygenase and the subsequent formation of thromboxane A2. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47526 |
|
| CAS_Registry |
41340-25-4 |
|
| CHEBI_ID |
CHEBI:4909 |
|
| Chemical_Formula |
C17H21NO3 |
|
| code |
C47526 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA |
|
| DEFINITION |
A pyranocarboxylic acid and non-steroidal anti-inflammatory drug (NSAID) with antipyretic and analgesic activities. Etodolac inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, and inflammation. It also inhibits platelet aggregation by blocking platelet cyclooxygenase and the subsequent formation of thromboxane A2. |
|
| Display_Name |
Etodolac |
|
| FDA_UNII_Code |
2M36281008 |
|
| FULL_SYN |
1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic Acid Etodolic Acid ETODOLAC Etodolac Lodine Ultradol |
|
| Has_Target | ||
| label |
Etodolac |
|
| Legacy Concept Name |
Etodolac |
|
| NCI_Drug_Dictionary_ID |
561499 |
|
| NSC Number |
282126 |
|
| PDQ_Closed_Trial_Search_ID |
561499 |
|
| PDQ_Open_Trial_Search_ID |
561499 |
|
| Preferred_Name |
Etodolac |
|
| prefixIRI |
Thesaurus:C47526 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0059865 |
|
| subClassOf |