Link to this page
National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
Jump to:
| Preferred Name | Escitalopram Oxalate | |
| Synonyms |
escitalopram ESCITALOPRAM OXALATE Lu 26-054-0 5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-,(1S)-, ethanedioate(1:1) Escitalopram Oxalate Lexapro |
|
| Definitions |
The oxalate salt of escitalopram, a pure S-enantiomer of the racemic bicyclic phthalane derivative citalopram, with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), escitalopram blocks the reuptake of serotonin by neurons in the central nervous system (CNS), thereby potentiating CNS serotonergic activity. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47518 |
|
| Accepted_Therapeutic_Use_For |
Major Depressive Disorder in Adolescents
|
|
| ALT_DEFINITION |
A drug used to treat depression and certain anxiety disorders. It belongs to the family of drugs called selective serotonin reuptake inhibitors (SSRIs).
|
|
| CAS_Registry |
219861-08-2
|
|
| Chemical_Formula |
C20H21FN2O.C2H2O4
|
|
| code |
C47518
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA
|
|
| DEFINITION |
The oxalate salt of escitalopram, a pure S-enantiomer of the racemic bicyclic phthalane derivative citalopram, with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), escitalopram blocks the reuptake of serotonin by neurons in the central nervous system (CNS), thereby potentiating CNS serotonergic activity.
|
|
| Display_Name |
Escitalopram Oxalate
|
|
| FDA_UNII_Code |
5U85DBW7LO
|
|
| FULL_SYN |
escitalopram ESCITALOPRAM OXALATE Lu 26-054-0 5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-,(1S)-, ethanedioate(1:1) Escitalopram Oxalate Lexapro
|
|
| Has_Free_Acid_Or_Base_Form | ||
| Has_Target | ||
| label |
Escitalopram Oxalate
|
|
| Legacy Concept Name |
Escitalopram_Oxalate
|
|
| NCI_Drug_Dictionary_ID |
497135
|
|
| PDQ_Closed_Trial_Search_ID |
497135
|
|
| PDQ_Open_Trial_Search_ID |
497135
|
|
| Preferred_Name |
Escitalopram Oxalate
|
|
| prefixIRI |
Thesaurus:C47518
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C1170746
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping