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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Eptifibatide | |
| Synonyms |
Eptifibatide EPTIFIBATIDE L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-, cyclic(1-6)-disulfide Integrilin |
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| Definitions |
A cyclical heptapeptide with anticoagulant activity. Eptifibatide selectively and reversibly binds to and blocks the platelet glycoprotein IIb/IIIa receptor. This prevents the binding of fibrinogen, von Willebrand factor, and other adhesive ligands and leads to an inhibition of platelet aggregation and prevents thrombus development. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47516 |
|
| CAS_Registry |
148031-34-9 188627-80-7
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|
| CHEBI_ID |
CHEBI:291902
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|
| Chemical_Formula |
C35H49N11O9S2
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|
| code |
C47516
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA HemOnc
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|
| DEFINITION |
A cyclical heptapeptide with anticoagulant activity. Eptifibatide selectively and reversibly binds to and blocks the platelet glycoprotein IIb/IIIa receptor. This prevents the binding of fibrinogen, von Willebrand factor, and other adhesive ligands and leads to an inhibition of platelet aggregation and prevents thrombus development.
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|
| FDA_UNII_Code |
NA8320J834
|
|
| FULL_SYN |
Eptifibatide EPTIFIBATIDE L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-, cyclic(1-6)-disulfide Integrilin
|
|
| label |
Eptifibatide
|
|
| Legacy Concept Name |
Eptifibatide
|
|
| Preferred_Name |
Eptifibatide
|
|
| prefixIRI |
Thesaurus:C47516
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|
| Semantic_Type |
Pharmacologic Substance
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|
| UMLS_CUI |
C0253563
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|
| subClassOf |
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