National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Enflurane

Synonyms

2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane

Methylflurether

2-Chloro-1,1,2-trifluoroethyl difluoromethyl Ether

ENFLURANE

Enflurane

Ethrane

Definitions

A fluorinated ether and very potent and stable general anaesthetic agent. The mechanism through which enflurane exerts its effect is not clear, it probably acts on nerve cell membranes to disrupt neuronal transmission in the brain, probably via an action at the lipid matrix of the neuronal membrane. Enflurane may also enhance the activity of the inhibitory neurotransmitter gamma-aminobutyric acid on synaptic transmission. Enflurane may also inhibit glutamatergic excitatory transmission.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47511

CAS_Registry

13838-16-9

CHEBI_ID

CHEBI:4792

Chemical_Formula

C3H2ClF5O

code

C47511

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A fluorinated ether and very potent and stable general anaesthetic agent. The mechanism through which enflurane exerts its effect is not clear, it probably acts on nerve cell membranes to disrupt neuronal transmission in the brain, probably via an action at the lipid matrix of the neuronal membrane. Enflurane may also enhance the activity of the inhibitory neurotransmitter gamma-aminobutyric acid on synaptic transmission. Enflurane may also inhibit glutamatergic excitatory transmission.

FDA_UNII_Code

91I69L5AY5

FULL_SYN

2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane

Methylflurether

2-Chloro-1,1,2-trifluoroethyl difluoromethyl Ether

ENFLURANE

Enflurane

Ethrane

label

Enflurane

Legacy Concept Name

Enflurane

NSC Number

115944

Preferred_Name

Enflurane

prefixIRI

Thesaurus:C47511

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0014277

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C245

Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_4792 CHEBI LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016610 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/LNC/LP18610-3 LOINC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387176008 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/NCIT_C47511 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D004737 RH-MESH LOOM
http://purl.obolibrary.org/obo/MESH_D004737 BERO LOOM
http://www.drugbank.ca/drugs/DB00228 FTC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.355.601.400 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0014277 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/3920 RXNORM LOOM
http://purl.bioontology.org/ontology/SNMI/C-6A114 SNMI LOOM
http://purl.bioontology.org/ontology/MESH/D004737 MESH LOOM
https://go.drugbank.com/drugs/DB00228 MDM LOOM
http://purl.bioontology.org/ontology/RCD/o22.. RCD LOOM
http://purl.bioontology.org/ontology/NDDF/001390 NDDF LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004794 LOINC LOOM
http://purl.bioontology.org/ontology/ATC/N01AB04 ATC LOOM
http://purl.obolibrary.org/obo/CHEBI_4792 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_4792 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_4792 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_4792 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_4792 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_4792 NIFSTD LOOM
http://purl.bioontology.org/ontology/VANDF/4019106 VANDF LOOM
http://purl.jp/bio/4/id/200906023039535803 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147363 NDFRT LOOM
http://stirdf.jst.go.jp/id/200907080280676857 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#4485 OCHV LOOM
http://purl.obolibrary.org/obo/dinto_DB00228 DINTO LOOM
http://purl.bioontology.org/ontology/CSP/1372-8093 CRISP LOOM
http://purl.obolibrary.org/obo/OMIT_0005980 OMIT LOOM
http://www.co-ode.org/ontologies/galen#Enflurane GALEN LOOM