Link to this page
National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
Jump to:
| Preferred Name | Dyphylline | |
| Synonyms |
7-(2,3-Dioxypropyl)theophylline 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl Diprophylline Neothylline DYPHYLLINE Dilor Dylix Dyphylline Lufyllin |
|
| Definitions |
A xanthine derivative. Dyphilline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP. This results in relaxation of bronchial smooth muscle and other smooth muscles. Dyphylline may also antagonize adenosine receptors. Dyphylline is used in the treatment of acute bronchial asthma, chronic bronchitis and emphysema. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47504 |
|
| CAS_Registry |
479-18-5
|
|
| CHEBI_ID |
CHEBI:4728
|
|
| Chemical_Formula |
C10H14N4O4
|
|
| code |
C47504
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
A xanthine derivative. Dyphilline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP. This results in relaxation of bronchial smooth muscle and other smooth muscles. Dyphylline may also antagonize adenosine receptors. Dyphylline is used in the treatment of acute bronchial asthma, chronic bronchitis and emphysema.
|
|
| FDA_UNII_Code |
263T0E9RR9
|
|
| FULL_SYN |
7-(2,3-Dioxypropyl)theophylline 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl Diprophylline Neothylline DYPHYLLINE Dilor Dylix Dyphylline Lufyllin
|
|
| label |
Dyphylline
|
|
| Legacy Concept Name |
Dyphylline
|
|
| NSC Number |
14305
|
|
| Preferred_Name |
Dyphylline
|
|
| prefixIRI |
Thesaurus:C47504
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0013360
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping