Preferred Name | Dipivefrin Hydrochloride | |
Synonyms |
DIPIVEFRIN HYDROCHLORIDE Dipivefrin Hydrochloride (1)-4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylene Dipivalate Hydrochloride Propanoic Acid, 2,2-dimethyl-, 4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene Ester, Hydrochloride,(+-)- Alcon Propine |
|
Definitions |
An ester with sympathomimetic activities. Dipivefrin hydrochloride is a prodrug of epinephrine that, due to its greater lipophilicity, allows for better penetration into the anterior chamber. Once inside the eye, dipivefrin hydrochloride is converted by hydrolysis to epinephrine. Epinephrine enhances the outflow of aqueous humor and decreases the production of aqueous humor by vasoconstriction. This leads to a reduction in intraocular pressure. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47495 |
|
CAS_Registry |
64019-93-8 |
|
CHEBI_ID |
CHEBI:4647 |
|
Chemical_Formula |
C19H29NO5.HCl |
|
code |
C47495 |
|
Concept_In_Subset | ||
Contributing_Source |
FDA |
|
DEFINITION |
An ester with sympathomimetic activities. Dipivefrin hydrochloride is a prodrug of epinephrine that, due to its greater lipophilicity, allows for better penetration into the anterior chamber. Once inside the eye, dipivefrin hydrochloride is converted by hydrolysis to epinephrine. Epinephrine enhances the outflow of aqueous humor and decreases the production of aqueous humor by vasoconstriction. This leads to a reduction in intraocular pressure. |
|
FDA_UNII_Code |
5QTH9UHV0K |
|
FULL_SYN |
DIPIVEFRIN HYDROCHLORIDE Dipivefrin Hydrochloride (1)-4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylene Dipivalate Hydrochloride Propanoic Acid, 2,2-dimethyl-, 4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene Ester, Hydrochloride,(+-)- Alcon Propine |
|
Has_Free_Acid_Or_Base_Form | ||
label |
Dipivefrin Hydrochloride |
|
Legacy Concept Name |
Dipivefrin_Hydrochloride |
|
Preferred_Name |
Dipivefrin Hydrochloride |
|
prefixIRI |
Thesaurus:C47495 |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0700488 |
|
subClassOf |