loading...| Preferred Name |
Dexchlorpheniramine Maleate |
|
| Synonyms |
DEXCHLORPHENIRAMINE MALEATE (+)-2-(p-Chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine Maleate(1:1) S-(+)-Chlorpheniramine Maleate d-Chlorpheniramine Maleate Dexchlorpheniramine Maleate (gamma-(4-Chlorophenyl)-pyridine-2-propyl)(dimethyl)ammonium hydrogen(Z)-maleate Mylaramine Polaramine |
|
| Definitions |
The maleate salt form of dexchlorpheniramine, an alkylamine, and first-generation histamine antagonist with anti-allergic activity. Dexchlorpheniramine maleate competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47478 |
|
| CAS_Registry |
2438-32-6 |
|
| Chemical_Formula |
C16H19ClN2.C4H4O4 |
|
| code |
C47478 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The maleate salt form of dexchlorpheniramine, an alkylamine, and first-generation histamine antagonist with anti-allergic activity. Dexchlorpheniramine maleate competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms. |
|
| FDA_UNII_Code |
B10YD955QW |
|
| FULL_SYN |
DEXCHLORPHENIRAMINE MALEATE (+)-2-(p-Chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine Maleate(1:1) S-(+)-Chlorpheniramine Maleate d-Chlorpheniramine Maleate Dexchlorpheniramine Maleate (gamma-(4-Chlorophenyl)-pyridine-2-propyl)(dimethyl)ammonium hydrogen(Z)-maleate Mylaramine Polaramine |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Dexchlorpheniramine Maleate |
|
| Legacy Concept Name |
Dexchlorpheniramine_Maleate |
|
| Preferred_Name |
Dexchlorpheniramine Maleate |
|
| prefixIRI |
Thesaurus:C47478 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0137440 |
|
| subClassOf |