National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Preferred Name

Desloratadine
Synonyms

DESLORATADINE

Desloratadine

5H-Benzo(5,6)cyclohepta(1,2-b)pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-

Clarinex

Sch 34117
Definitions

A long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching and spasmodic contractions of gastrointestinal smooth muscle. Desloratadine is used to provide symptomatic relieve of allergic symptoms.
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47474
CAS_Registry

100643-71-8
CHEBI_ID

CHEBI:291342
Chemical_Formula

C19H19ClN2
code

C47474
Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923
Contributing_Source

FDA
DEFINITION

A long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching and spasmodic contractions of gastrointestinal smooth muscle. Desloratadine is used to provide symptomatic relieve of allergic symptoms.
FDA_UNII_Code

FVF865388R
FULL_SYN

DESLORATADINE

Desloratadine

5H-Benzo(5,6)cyclohepta(1,2-b)pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-

Clarinex

Sch 34117
label

Desloratadine
Legacy Concept Name

Desloratadine
Preferred_Name

Desloratadine
prefixIRI

Thesaurus:C47474
Semantic_Type

Pharmacologic Substance
UMLS_CUI

C0908935
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29578
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