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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Clemastine Fumarate | |
| Synonyms |
Clemastine Fumarate Mecloprodine CLEMASTINE FUMARATE (+)-2-(2-((p-Chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methyl Pyrrolidine Fumarate Agasten Clemanil Tavist Xolamin |
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| Definitions |
A synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties. Clemastine fumarate blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial and gastrointestinal smooth muscles, including vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscles. This drug also prevents histamine-induced pain and itching of mucous membranes. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47454 |
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| CAS_Registry |
14976-57-9
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|
| CHEBI_ID |
CHEBI:3739
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| Chemical_Formula |
C21H26ClNO.C4H4O4
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|
| code |
C47454
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| Concept_In_Subset | ||
| Contributing_Source |
FDA
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|
| DEFINITION |
A synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties. Clemastine fumarate blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial and gastrointestinal smooth muscles, including vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscles. This drug also prevents histamine-induced pain and itching of mucous membranes.
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| FDA_UNII_Code |
19259EGQ3D
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|
| FULL_SYN |
Clemastine Fumarate Mecloprodine CLEMASTINE FUMARATE (+)-2-(2-((p-Chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methyl Pyrrolidine Fumarate Agasten Clemanil Tavist Xolamin
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Clemastine Fumarate
|
|
| Legacy Concept Name |
Clemastine_Fumarate
|
|
| Preferred_Name |
Clemastine Fumarate
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|
| prefixIRI |
Thesaurus:C47454
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|
| Semantic_Type |
Pharmacologic Substance
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|
| UMLS_CUI |
C0546858
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|
| subClassOf |
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