National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Chloroxine

Synonyms

5,7-Dichloro-8-hydroxyquinoline

CHLOROXINE

Capitrol

Chloroxine

Definitions

A synthetic quinoline derivative with antibacterial activity. Although the mechanism of action is not fully understood, topical administration of chloroxine diminishes mitotic activity in the epidermis, thereby reducing excessive scaling associated with dandruff or seborrheic dermatitis of the scalp, including psoriasis and eczema.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47446

CAS_Registry

773-76-2

CHEBI_ID

CHEBI:59477

Chemical_Formula

C9H5Cl2NO

code

C47446

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic quinoline derivative with antibacterial activity. Although the mechanism of action is not fully understood, topical administration of chloroxine diminishes mitotic activity in the epidermis, thereby reducing excessive scaling associated with dandruff or seborrheic dermatitis of the scalp, including psoriasis and eczema.

FDA_UNII_Code

2I8BD50I8B

FULL_SYN

5,7-Dichloro-8-hydroxyquinoline

CHLOROXINE

Capitrol

Chloroxine

label

Chloroxine

Legacy Concept Name

Chloroxine

NSC Number

3904

Preferred_Name

Chloroxine

prefixIRI

Thesaurus:C47446

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0055461

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29708

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