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National Cancer Institute Thesaurus
| Preferred Name | Cephapirin Sodium | |
| Synonyms |
Cephapirin Sodium 7-(alpha-(4-Pyridylthio)acetamido)cephalosporanic acid sodium salt Sodium (6R-trans)-3-(Acetoxymethyl)-8-oxo-7-((4-pyridylthio)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate 5-Thia-1-azabicyclo(4,2,0)oct-2-ene-2-carboxylic acid, 3-(hydroxymethyl)-8-oxo-7-(2-(4-pyridylthio)acetamido)-, Acetate (Ester), Monosodium Salt Cephatrexil Sodium; (6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-pyridin-4-ylsulfanylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate CEPHAPIRIN SODIUM Bristocef Cefadyl Cefalak |
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| Definitions |
The sodium salt form of cephapirin, a semi-synthetic, broad-spectrum, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephapirin sodium inhibits bacterial cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis and subsequent cross-linking of peptidoglycan units. This results in a reduction of cell wall stability and leads to cell lysis. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47440 |
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| CAS_Registry |
24356-60-3
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| CHEBI_ID |
CHEBI:3545
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| Chemical_Formula |
C17H16N3O6S2.Na
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| code |
C47440
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| Concept_In_Subset | ||
| Contributing_Source |
FDA
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| DEFINITION |
The sodium salt form of cephapirin, a semi-synthetic, broad-spectrum, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephapirin sodium inhibits bacterial cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis and subsequent cross-linking of peptidoglycan units. This results in a reduction of cell wall stability and leads to cell lysis.
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| FDA_UNII_Code |
431LFF7I7J
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| FULL_SYN |
Cephapirin Sodium 7-(alpha-(4-Pyridylthio)acetamido)cephalosporanic acid sodium salt Sodium (6R-trans)-3-(Acetoxymethyl)-8-oxo-7-((4-pyridylthio)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate 5-Thia-1-azabicyclo(4,2,0)oct-2-ene-2-carboxylic acid, 3-(hydroxymethyl)-8-oxo-7-(2-(4-pyridylthio)acetamido)-, Acetate (Ester), Monosodium Salt Cephatrexil Sodium; (6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-pyridin-4-ylsulfanylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate CEPHAPIRIN SODIUM Bristocef Cefadyl Cefalak
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| Has_Free_Acid_Or_Base_Form | ||
| label |
Cephapirin Sodium
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| Legacy Concept Name |
Cephapirin_Sodium
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| NSC Number |
179171
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| Preferred_Name |
Cephapirin Sodium
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| prefixIRI |
Thesaurus:C47440
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0085905
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| subClassOf |
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