National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Carbachol
Synonyms

2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminium Chloride

Isopto Carbachol

CARBACHOL

Carbachol

Carbastat

Carboptic

Miostat

Definitions

A synthetic choline ester and a positively charged quaternary ammonium compound. Carbachol is a parasympathomimetic that mimics the effect of acetylcholine on both the muscarinic and nicotinic receptors. This drug is administered ocularly to induce miosis to reduce intraocular pressure in the treatment of glaucoma. Carbachol is also used to stimulate micturition by contraction of detrusor muscle. This drug may cause hypotension, bradycardia, nausea, vomiting, bronchospasm, and abdominal cramps.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47430

CAS_Registry

51-83-2

CHEBI_ID

CHEBI:3385

Chemical_Formula

C6H15N2O2.Cl

code

C47430

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic choline ester and a positively charged quaternary ammonium compound. Carbachol is a parasympathomimetic that mimics the effect of acetylcholine on both the muscarinic and nicotinic receptors. This drug is administered ocularly to induce miosis to reduce intraocular pressure in the treatment of glaucoma. Carbachol is also used to stimulate micturition by contraction of detrusor muscle. This drug may cause hypotension, bradycardia, nausea, vomiting, bronchospasm, and abdominal cramps.

FDA_UNII_Code

8Y164V895Y

FULL_SYN

2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminium Chloride

Isopto Carbachol

CARBACHOL

Carbachol

Carbastat

Carboptic

Miostat

label

Carbachol

Legacy Concept Name

Carbachol

NSC Number

32865

Preferred_Name

Carbachol

prefixIRI

Thesaurus:C47430

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0306489

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29705

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_3385 DRON LOOM
http://purl.obolibrary.org/obo/OMIT_0003556 OMIT LOOM
http://purl.bioontology.org/ontology/RXNORM/1999 RXNORM LOOM
http://www.bioassayontology.org/bao#BAO_0000876 BAO LOOM
http://purl.bioontology.org/ontology/ATC/S01EB02 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387183001 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/RCD/x02MH RCD LOOM
http://localhost/plosthes.2017-1#6119 PLOSTHES LOOM
http://purl.obolibrary.org/obo/XCO_0000692 XCO LOOM
http://www.co-ode.org/ontologies/galen#Carbachol GALEN LOOM
http://purl.obolibrary.org/obo/MESH_D002217 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.877.883.333.115 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-97720 SNMI LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146899 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002217 RH-MESH LOOM
http://purl.bioontology.org/ontology/CSP/0663-1356 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.675.276.232.115 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/001690 NDDF LOOM
http://purl.obolibrary.org/obo/CHEBI_3385 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_3385 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_3385 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3385 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_3385 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_3385 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3385 NIFSTD LOOM
http://stirdf.jst.go.jp/id/200907035496188975 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0006945 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2379 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4018583 VANDF LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Carbachol APAONTO LOOM
http://www.drugbank.ca/drugs/DB00411 FTC LOOM
http://purl.obolibrary.org/obo/NCIT_C47430 BERO LOOM
http://purl.jp/bio/4/id/200906093121951309 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/D002217 MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016058 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/ATC/N07AB01 ATC LOOM