National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Brompheniramine Maleate
Synonyms

2-(p-Bromo-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine Maleate

BROMPHENIRAMINE MALEATE

2-Pyridinepropanamine, gamma-(4-bromophenyl)-N,N-dimethyl-, (Z)-butenedioate (1:1)

2-Pyridinepropanamine, gamma-(4-Bromophenyl)-N,N-dimethyl-,(Z)-butenedioate(1:1)

Brompheniramine Maleate

Parabromdylamine Maleate

Allent

Dimetane

Drauxin

Ilvin

Nagemid

Definitions

The maleate salt form of brompheniramine, an alkylamine derivative and a histamine antagonist with anticholinergic and sedative properties. Brompheniramine maleate competes with histamine for the H1 receptor. This diminishes the actions of histamine on effector cells and decreases the histamine-mediated symptoms of allergic reaction such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47422

CAS_Registry

980-71-2

CHEBI_ID

CHEBI:3184

Chemical_Formula

C16H19BrN2.C4H4O4

code

C47422

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The maleate salt form of brompheniramine, an alkylamine derivative and a histamine antagonist with anticholinergic and sedative properties. Brompheniramine maleate competes with histamine for the H1 receptor. This diminishes the actions of histamine on effector cells and decreases the histamine-mediated symptoms of allergic reaction such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle.

FDA_UNII_Code

IXA7C9ZN03

FULL_SYN

2-(p-Bromo-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine Maleate

BROMPHENIRAMINE MALEATE

2-Pyridinepropanamine, gamma-(4-bromophenyl)-N,N-dimethyl-, (Z)-butenedioate (1:1)

2-Pyridinepropanamine, gamma-(4-Bromophenyl)-N,N-dimethyl-,(Z)-butenedioate(1:1)

Brompheniramine Maleate

Parabromdylamine Maleate

Allent

Dimetane

Drauxin

Ilvin

Nagemid

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61655

label

Brompheniramine Maleate

Legacy Concept Name

Brompheniramine_Maleate

Preferred_Name

Brompheniramine Maleate

prefixIRI

Thesaurus:C47422

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0546853

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29578

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