loading...| Preferred Name |
Brimonidine Tartrate |
|
| Synonyms |
6-Quinoxalinamine, 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-,(2R,3R)-2,3-dihydroxybutanedioate(1:1) BRIMONIDINE TARTRATE Brimonidine Tartrate Alphagan |
|
| Definitions |
The tartrate salt form of brimonidine, an imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine tartrate acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine tartrate also enhances the outflow of aqueous humor. This drug is used in the treatment of glaucoma to reduce intraocular pressure. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47419 |
|
| CAS_Registry |
70359-46-5 79570-19-7 |
|
| CHEBI_ID |
CHEBI:51157 |
|
| Chemical_Formula |
C11H10BrN5.C4H6O6 |
|
| code |
C47419 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA |
|
| DEFINITION |
The tartrate salt form of brimonidine, an imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine tartrate acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine tartrate also enhances the outflow of aqueous humor. This drug is used in the treatment of glaucoma to reduce intraocular pressure. |
|
| Display_Name |
Brimonidine Tartrate |
|
| FDA_UNII_Code |
4S9CL2DY2H |
|
| FULL_SYN |
6-Quinoxalinamine, 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-,(2R,3R)-2,3-dihydroxybutanedioate(1:1) BRIMONIDINE TARTRATE Brimonidine Tartrate Alphagan |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Brimonidine Tartrate |
|
| Legacy Concept Name |
Brimonidine_Tartrate |
|
| NCI_Drug_Dictionary_ID |
786307 |
|
| PDQ_Closed_Trial_Search_ID |
786307 |
|
| PDQ_Open_Trial_Search_ID |
786307 |
|
| Preferred_Name |
Brimonidine Tartrate |
|
| prefixIRI |
Thesaurus:C47419 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0077768 |
|
| subClassOf |