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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Brimonidine Tartrate | |
| Synonyms |
6-Quinoxalinamine, 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-,(2R,3R)-2,3-dihydroxybutanedioate(1:1) BRIMONIDINE TARTRATE Brimonidine Tartrate Alphagan |
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| Definitions |
The tartrate salt form of brimonidine, an imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine tartrate acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine tartrate also enhances the outflow of aqueous humor. This drug is used in the treatment of glaucoma to reduce intraocular pressure. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47419 |
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| CAS_Registry |
70359-46-5 79570-19-7
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|
| CHEBI_ID |
CHEBI:51157
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|
| Chemical_Formula |
C11H10BrN5.C4H6O6
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|
| code |
C47419
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|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
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| Contributing_Source |
CTRP FDA
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|
| DEFINITION |
The tartrate salt form of brimonidine, an imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine tartrate acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine tartrate also enhances the outflow of aqueous humor. This drug is used in the treatment of glaucoma to reduce intraocular pressure.
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|
| Display_Name |
Brimonidine Tartrate
|
|
| FDA_UNII_Code |
4S9CL2DY2H
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|
| FULL_SYN |
6-Quinoxalinamine, 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-,(2R,3R)-2,3-dihydroxybutanedioate(1:1) BRIMONIDINE TARTRATE Brimonidine Tartrate Alphagan
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Brimonidine Tartrate
|
|
| Legacy Concept Name |
Brimonidine_Tartrate
|
|
| NCI_Drug_Dictionary_ID |
786307
|
|
| PDQ_Closed_Trial_Search_ID |
786307
|
|
| PDQ_Open_Trial_Search_ID |
786307
|
|
| Preferred_Name |
Brimonidine Tartrate
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|
| prefixIRI |
Thesaurus:C47419
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|
| Semantic_Type |
Pharmacologic Substance
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|
| UMLS_CUI |
C0077768
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| subClassOf |
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