National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Epichlorohydrin

Synonyms

Epichlorhydrin

EPICHLOROHYDRIN

Epichlorohydrin

3-Chloro-1,2-propylene Oxide

1-Chloro-2,3-epoxypropane

Chloromethyloxirane

dl-a-Epichlorohydrin

Chloromethylethylene Oxide

(RS)-3-Chloro-1,2-epoxypropane

NCI-CO7001

Definitions

A volatile and flammable, clear, colorless, liquid, chlorinated cyclic ether with an irritating, chloroform-like odor that emits toxic fumes of hydrochloric acid and other chlorinated compounds when heated to decomposition. Epichlorohydrin is used in the manufacture of epoxy resins, synthetic glycerin and elastomers. Exposure to epichlorohydrin irritates the eyes, skin and respiratory tract, and can cause chemical pneumonitis, pulmonary edema, and renal lesions. This substance also affects the blood. Epichlorohydrin is reasonably anticipated to be a human carcinogen and may be associated with an increased risk of developing respiratory cancer. (NCI05)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C44381

CAS_Registry

106-89-8

CHEBI_ID

CHEBI:37144

Chemical_Formula

C3H5ClO

code

C44381

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A volatile and flammable, clear, colorless, liquid, chlorinated cyclic ether with an irritating, chloroform-like odor that emits toxic fumes of hydrochloric acid and other chlorinated compounds when heated to decomposition. Epichlorohydrin is used in the manufacture of epoxy resins, synthetic glycerin and elastomers. Exposure to epichlorohydrin irritates the eyes, skin and respiratory tract, and can cause chemical pneumonitis, pulmonary edema, and renal lesions. This substance also affects the blood. Epichlorohydrin is reasonably anticipated to be a human carcinogen and may be associated with an increased risk of developing respiratory cancer. (NCI05)

FDA_UNII_Code

08OOR508C0

FULL_SYN

Epichlorhydrin

EPICHLOROHYDRIN

Epichlorohydrin

3-Chloro-1,2-propylene Oxide

1-Chloro-2,3-epoxypropane

Chloromethyloxirane

dl-a-Epichlorohydrin

Chloromethylethylene Oxide

(RS)-3-Chloro-1,2-epoxypropane

NCI-CO7001

label

Epichlorohydrin

Legacy Concept Name

Epichlorohydrin

NSC Number

6747

Preferred_Name

Epichlorohydrin

prefixIRI

Thesaurus:C44381

Semantic_Type

Hazardous or Poisonous Substance

UMLS_CUI

C0014486

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45408

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