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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Dextromethorphan Hydrobromide | |
| Synonyms |
Dextromethorphan Hydrobromide DEXTROMETHORPHAN HYDROBROMIDE |
|
| Definitions |
The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C423 |
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| CAS_Registry |
6700-34-1
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|
| Chemical_Formula |
C18H25NO.BrH.H2O
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|
| code |
C423
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|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
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| Contributing_Source |
CTRP FDA
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|
| DEFINITION |
The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.
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|
| Display_Name |
Dextromethorphan Hydrobromide
|
|
| FDA_UNII_Code |
9D2RTI9KYH
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|
| FULL_SYN |
Dextromethorphan Hydrobromide DEXTROMETHORPHAN HYDROBROMIDE
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Dextromethorphan Hydrobromide
|
|
| Legacy Concept Name |
Dextromethorphan
|
|
| NCI_Drug_Dictionary_ID |
42490
|
|
| PDQ_Closed_Trial_Search_ID |
42490
|
|
| PDQ_Open_Trial_Search_ID |
42490
|
|
| Preferred_Name |
Dextromethorphan Hydrobromide
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|
| prefixIRI |
Thesaurus:C423
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
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|
| UMLS_CUI |
C0350422
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|
| subClassOf |
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