loading...| Preferred Name |
Cyproterone |
|
| Synonyms |
Cyproterone CYPROTERONE Med Cyproterone SH-881 |
|
| Definitions |
A synthetic steroidal anti-androgen with antineoplastic activity. Cyproterone, in its acetate form, binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation and inhibiting the growth of testosterone-sensitive tumor cells. This agent also exerts progesterogenic activity, resulting in a reduction in testicular androgen secretion and total androgen blockade. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C407 |
|
| CAS_Registry |
2098-66-0 |
|
| CHEBI_ID |
CHEBI:50742 |
|
| Chemical_Formula |
C22H27ClO3 |
|
| code |
C407 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
|
| Contributing_Source |
FDA GDC |
|
| DEFINITION |
A synthetic steroidal anti-androgen with antineoplastic activity. Cyproterone, in its acetate form, binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation and inhibiting the growth of testosterone-sensitive tumor cells. This agent also exerts progesterogenic activity, resulting in a reduction in testicular androgen secretion and total androgen blockade. (NCI04) |
|
| FDA_UNII_Code |
E61Q31EK2F |
|
| FULL_SYN |
Cyproterone CYPROTERONE Med Cyproterone SH-881 |
|
| Has_Salt_Form | ||
| Has_Target | ||
| Is_Value_For_GDC_Property | ||
| label |
Cyproterone |
|
| Legacy Concept Name |
Cyproterone |
|
| Maps_To |
Cyproterone |
|
| Preferred_Name |
Cyproterone |
|
| prefixIRI |
Thesaurus:C407 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0010621 |
|
| subClassOf |