loading...| Preferred Name |
Troponin T |
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| Synonyms |
TNNT Troponin T |
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| Definitions |
Troponin I, troponin T, and troponin C are the three closely associated subunits of the troponin complex of thin filaments in muscle. The complex serves as a calcium-sensitive switch that regulates muscle contraction. Troponin T binds tropomyosin to the troponin complex and inhibits F-actin-myosin interactions. The troponin T gene family comprises three isoforms: slow skeletal (TNNT1), cardiac (TNNT2) and fast skeletal (TNNT3). Because it is not normally found in blood, cardiac troponin-T in serum is a sensitive indicator of myocardial cell injury. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38041 |
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| code |
C38041 |
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| DEFINITION |
Troponin I, troponin T, and troponin C are the three closely associated subunits of the troponin complex of thin filaments in muscle. The complex serves as a calcium-sensitive switch that regulates muscle contraction. Troponin T binds tropomyosin to the troponin complex and inhibits F-actin-myosin interactions. The troponin T gene family comprises three isoforms: slow skeletal (TNNT1), cardiac (TNNT2) and fast skeletal (TNNT3). Because it is not normally found in blood, cardiac troponin-T in serum is a sensitive indicator of myocardial cell injury. |
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| FULL_SYN |
TNNT Troponin T |
|
| label |
Troponin T |
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| Legacy Concept Name |
Troponin_T |
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| Preferred_Name |
Troponin T |
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| prefixIRI |
Thesaurus:C38041 |
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| Semantic_Type |
Amino Acid, Peptide, or Protein |
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| UMLS_CUI |
C0077404 |
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| subClassOf |