Preferred Name |
Capsaicin |
|
Synonyms |
N-(4-hydroxy-3-methoxyphenylmethyl) -8-Methyl-6-Nonenamide (E)-N-[(4-hydroxy-3-methoxy-phenyl)methyl]-8-methyl-non-6-enamide (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide CAPSAICIN Capsaicin capsaicin |
|
Definitions |
A chili pepper extract with analgesic properties. Capsaicin is a neuropeptide releasing agent selective for primary sensory peripheral neurons. Used topically, capsaicin aids in controlling peripheral nerve pain. This agent has been used experimentally to manipulate substance P and other tachykinins. In addition, capsaicin may be useful in controlling chemotherapy- and radiotherapy-induced mucositis. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C339 |
|
ALT_DEFINITION |
A component of certain plants, including cayenne and red pepper, used topically for peripheral nerve pain. Also being studied for controlling mucositis pain after chemotherapy and radiation therapy. Capsaicinoid compound with side chain CO(CH2)4(CH)2CH(CH3)2. The chemical structure is CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC. |
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CAS_Registry |
404-86-4 |
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CHEBI_ID |
CHEBI:3374 |
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Chemical_Formula |
C18H27NO3 |
|
code |
C339 |
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Concept_In_Subset | ||
Contributing_Source |
CRCH FDA |
|
DEFINITION |
A chili pepper extract with analgesic properties. Capsaicin is a neuropeptide releasing agent selective for primary sensory peripheral neurons. Used topically, capsaicin aids in controlling peripheral nerve pain. This agent has been used experimentally to manipulate substance P and other tachykinins. In addition, capsaicin may be useful in controlling chemotherapy- and radiotherapy-induced mucositis. |
|
FDA_UNII_Code |
S07O44R1ZM |
|
FULL_SYN |
N-(4-hydroxy-3-methoxyphenylmethyl) -8-Methyl-6-Nonenamide (E)-N-[(4-hydroxy-3-methoxy-phenyl)methyl]-8-methyl-non-6-enamide (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide CAPSAICIN Capsaicin capsaicin |
|
label |
Capsaicin |
|
Legacy Concept Name |
Capsaicin |
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NCI_Drug_Dictionary_ID |
41591 |
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NSC Number |
56353 |
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PDQ_Closed_Trial_Search_ID |
41591 |
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PDQ_Open_Trial_Search_ID |
41591 |
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Preferred_Name |
Capsaicin |
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prefixIRI |
Thesaurus:C339 |
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Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
UMLS_CUI |
C0006931 |
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subClassOf |