Preferred Name |
Leydig Cell Tumor |
|
Synonyms |
Interstitial Cell Tumor Interstitial Cell Neoplasm Leydig Cell Neoplasm Leydig Cell Tumor |
|
Definitions |
A sex cord-stromal tumor occurring in the testis and rarely in the ovary. It is predominantly or completely composed of Leydig cells which may contain crystals of Reinke. In males it usually presents as a painless testicular enlargement and it may be associated with gynecomastia and decreased libido. The majority of the cases have a benign clinical course. Approximately 10% of the cases have a malignant clinical course and metastasize. In females it may be associated with androgenic manifestations and it follows a benign clinical course. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3188 |
|
ALT_DEFINITION |
A sex cord-stromal tumor, comprising Leydig cells, either predominantly or completely, occurring in the testis and rarely in the ovary. |
|
code |
C3188 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168658 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118168 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132009 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168655 |
|
Contributing_Source |
CTRP GDC NICHD |
|
DEFINITION |
A sex cord-stromal tumor occurring in the testis and rarely in the ovary. It is predominantly or completely composed of Leydig cells which may contain crystals of Reinke. In males it usually presents as a painless testicular enlargement and it may be associated with gynecomastia and decreased libido. The majority of the cases have a benign clinical course. Approximately 10% of the cases have a malignant clinical course and metastasize. In females it may be associated with androgenic manifestations and it follows a benign clinical course. |
|
Display_Name |
Leydig Cell Tumor |
|
FULL_SYN |
Interstitial Cell Tumor Interstitial Cell Neoplasm Leydig Cell Neoplasm Leydig Cell Tumor |
|
ICD-O-3_Code |
8650/1 |
|
Is_Value_For_GDC_Property | ||
label |
Leydig Cell Tumor |
|
Legacy Concept Name |
Leydig_Cell_Tumor |
|
Maps_To |
Interstitial cell tumor, NOS Leydig cell tumor, NOS 8650/1 |
|
Neoplastic_Status |
Undetermined |
|
Preferred_Name |
Leydig Cell Tumor |
|
prefixIRI |
Thesaurus:C3188 |
|
Semantic_Type |
Neoplastic Process |
|
UMLS_CUI |
C0023601 |
|
subClassOf |