National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Leydig Cell Tumor

Synonyms

Interstitial Cell Tumor

Interstitial Cell Neoplasm

Leydig Cell Neoplasm

Leydig Cell Tumor

Definitions

A sex cord-stromal tumor occurring in the testis and rarely in the ovary. It is predominantly or completely composed of Leydig cells which may contain crystals of Reinke. In males it usually presents as a painless testicular enlargement and it may be associated with gynecomastia and decreased libido. The majority of the cases have a benign clinical course. Approximately 10% of the cases have a malignant clinical course and metastasize. In females it may be associated with androgenic manifestations and it follows a benign clinical course.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3188

ALT_DEFINITION

A sex cord-stromal tumor, comprising Leydig cells, either predominantly or completely, occurring in the testis and rarely in the ovary.

code

C3188

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168658

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118168

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132009

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168655

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168657

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

Contributing_Source

CTRP

GDC

NICHD

DEFINITION

A sex cord-stromal tumor occurring in the testis and rarely in the ovary. It is predominantly or completely composed of Leydig cells which may contain crystals of Reinke. In males it usually presents as a painless testicular enlargement and it may be associated with gynecomastia and decreased libido. The majority of the cases have a benign clinical course. Approximately 10% of the cases have a malignant clinical course and metastasize. In females it may be associated with androgenic manifestations and it follows a benign clinical course.

Display_Name

Leydig Cell Tumor

FULL_SYN

Interstitial Cell Tumor

Interstitial Cell Neoplasm

Leydig Cell Neoplasm

Leydig Cell Tumor

ICD-O-3_Code

8650/1

Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177621

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176985

label

Leydig Cell Tumor

Legacy Concept Name

Leydig_Cell_Tumor

Maps_To

Interstitial cell tumor, NOS

Leydig cell tumor, NOS

8650/1

Neoplastic_Status

Undetermined

Preferred_Name

Leydig Cell Tumor

prefixIRI

Thesaurus:C3188

Semantic_Type

Neoplastic Process

UMLS_CUI

C0023601

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3794

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/MONDO_0006266 MONDO LOOM
http://purl.obolibrary.org/obo/DOID_2696 DOID LOOM
rgo:17685 GAMUTS LOOM
rgo:17685 GAMUTS LOOM
http://www.ebi.ac.uk/efo/EFO_1000321 EFO LOOM
http://purl.obolibrary.org/obo/DOID_2696 DOID LOOM
http://purl.bioontology.org/ontology/MESH/D007984 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D007984 RH-MESH LOOM
http://www.gamuts.net/entity#Leydig_cell_tumor GAMUTS LOOM
http://purl.obolibrary.org/obo/OMIT_0009069 OMIT LOOM
http://purl.jp/bio/4/id/200906086135465834 IOBC LOOM
http://id.nlm.nih.gov/mesh/D007984 MDM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#7380 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C04.588.322.762.500.249 RH-MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C3188 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C04.588.945.440.915.500.249 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C12.294.260.937.500.249 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0023601 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C19.391.829.782.500.249 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00038004 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000686432 PDQ LOOM
http://purl.obolibrary.org/obo/MONDO_0006266 DOVES LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Leydig_Cell_Tumor CSEO LOOM
http://www.owl-ontologies.com/NPOntology.owl#DOID_2696 NATPRO LOOM
http://purl.obolibrary.org/obo/MPATH_328 MPATH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C04.557.475.750.847.249 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C12.758.409.937.500.249 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C19.344.762.500.249 RH-MESH LOOM
http://purl.obolibrary.org/obo/DOID_2696 DTO LOOM
http://purl.obolibrary.org/obo/DOID_2696 BAO LOOM
http://purl.obolibrary.org/obo/DOID_2696 HHEAR LOOM
http://purl.obolibrary.org/obo/DOID_2696 NIFSTD LOOM
http://purl.obolibrary.org/obo/DOID_2696 MIDO LOOM
http://purl.obolibrary.org/obo/DOID_2696 FNS-H LOOM