loading...| Preferred Name |
Triethylenemelamine |
|
| Synonyms |
TRIETHYLENEMELAMINE Triethylene Melamine Triethylenemelamine TEM Tretamine |
|
| Definitions |
A trisaziridine alkylating agent with antineoplastic and carcinogenic properties. Used to induce cancer in experimental animal models, triethylenemelamine ethylates DNA, resulting in inhibition of DNA replication, unscheduled DNA synthesis, chromosomal aberrations, and sister chromatid exchanges. This agent also exhibits reproductive toxicities. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29858 |
|
| CAS_Registry |
51-18-3 |
|
| CHEBI_ID |
CHEBI:27919 |
|
| Chemical_Formula |
C9H12N6 |
|
| code |
C29858 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
|
| Contributing_Source |
FDA GDC |
|
| DEFINITION |
A trisaziridine alkylating agent with antineoplastic and carcinogenic properties. Used to induce cancer in experimental animal models, triethylenemelamine ethylates DNA, resulting in inhibition of DNA replication, unscheduled DNA synthesis, chromosomal aberrations, and sister chromatid exchanges. This agent also exhibits reproductive toxicities. (NCI04) |
|
| FDA_UNII_Code |
F7IY6HZG9D |
|
| FULL_SYN |
TRIETHYLENEMELAMINE Triethylene Melamine Triethylenemelamine TEM Tretamine |
|
| Is_Value_For_GDC_Property | ||
| label |
Triethylenemelamine |
|
| Legacy Concept Name |
Triethylenemelamine |
|
| Maps_To |
Triethylenemelamine |
|
| NSC Number |
9706 |
|
| Preferred_Name |
Triethylenemelamine |
|
| prefixIRI |
Thesaurus:C29858 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0040975 |
|
| subClassOf |