National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Leucine
Synonyms

(S)-2-Amino-4-methylpentanoic acid

L-Leucine

LEUCINE

Leu

Leucine

Definitions

One of nine essential amino acids in humans (provided by food), Leucine is important for protein synthesis and many metabolic functions. Leucine contributes to regulation of blood-sugar levels; growth and repair of muscle and bone tissue; growth hormone production; and wound healing. Leucine also prevents breakdown of muscle proteins after trauma or severe stress and may be beneficial for individuals with phenylketonuria. Leucine is available in many foods and deficiency is rare. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29599

ALT_DEFINITION

Amino acid with side chain -CH2CH(CH3)2.

CAS_Registry

61-90-5

CHEBI_ID

CHEBI:15603

Chemical_Formula

C6H13NO2

code

C29599

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CRCH

CTRP

FDA

DEFINITION

One of nine essential amino acids in humans (provided by food), Leucine is important for protein synthesis and many metabolic functions. Leucine contributes to regulation of blood-sugar levels; growth and repair of muscle and bone tissue; growth hormone production; and wound healing. Leucine also prevents breakdown of muscle proteins after trauma or severe stress and may be beneficial for individuals with phenylketonuria. Leucine is available in many foods and deficiency is rare. (NCI04)

Display_Name

Leucine

Essential_Amino_Acid

Y

FDA_UNII_Code

GMW67QNF9C

FULL_SYN

(S)-2-Amino-4-methylpentanoic acid

L-Leucine

LEUCINE

Leu

Leucine

INFOODS

LEU_G

label

Leucine

Legacy Concept Name

Leucine

Macronutrient

Y

NSC Number

9252

Nutrient

Y

Preferred_Name

Leucine

prefixIRI

Thesaurus:C29599

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0023401

Unit

g

USDA_ID

504

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68442

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http://purl.obolibrary.org/obo/CHEBI_25017 OBA LOOM
http://purl.obolibrary.org/obo/SO_0001437 SO LOOM
http://purl.obolibrary.org/obo/SO_0001437 SO LOOM
http://purl.obolibrary.org/obo/SO_0001437 NIFSTD LOOM
http://purl.bioontology.org/ontology/RXNORM/6308 RXNORM LOOM
http://id.nlm.nih.gov/mesh/D007930 MDM LOOM
http://www.co-ode.org/ontologies/galen#Leucine GALEN LOOM
http://purl.org/sig/ont/fma/fma82757 FMA LOOM
http://purl.bioontology.org/ontology/RCD/X807P RCD LOOM
http://localhost/plosthes.2017-1#8010 PLOSTHES LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146995 NDFRT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/83797003 SNOMEDCT LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Leucine APAONTO LOOM
https://go.drugbank.com/drugs/DB00149 MDM LOOM
http://www.phoc.org.cn/pmo/class/PMO_00021263 PMAPP-PMO LOOM
http://www.co-ode.org/ontologies/amino-acid/2006/05/18/amino-acid.owl#L AMINO-ACID LOOM
http://purl.jp/bio/10/gmo/GMO_001411 GMO LOOM
http://purl.obolibrary.org/obo/OMIT_0009021 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.070.637 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003096 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D007930 RH-MESH LOOM
http://vocabs.lter-europe.net/EnvThes/20776 ENVTHES LOOM
http://purl.obolibrary.org/obo/NCIT_C29599 BERO LOOM
http://purl.bioontology.org/ontology/MESH/D007930 MESH LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_25017 NPO LOOM
http://purl.jp/bio/4/id/200906083956732920 IOBC LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 FOODON LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 INBANCIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 OCMR LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 ENVO LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 BIPON LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 CDNO LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 CIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 ONSTR LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 MCO LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 MAXO LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 ZP LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 FNS-H LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 NMDCO LOOM
http://purl.obolibrary.org/obo/CHEBI_25017 OBA LOOM
http://purl.bioontology.org/ontology/VANDF/4018684 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.142.441 RH-MESH LOOM
http://vocabs.lter-europe.net/EnvThes/USLterCV_296 ENVTHES LOOM
http://purl.bioontology.org/ontology/NDDF/005060 NDDF LOOM
http://purl.bioontology.org/ontology/LNC/LP15699-9 LOINC LOOM
http://purl.bioontology.org/ontology/SNMI/F-64310 SNMI LOOM
http://www.projecthalo.com/aura#Leucine AURA LOOM
http://purl.bioontology.org/ontology/CSP/0124-2988 CRISP LOOM
http://purl.obolibrary.org/obo/MESH_D007930 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#7325 OCHV LOOM
http://doe-generated-ontology.com/OntoAD#C0023401 ONTOAD LOOM
http://purl.org/obo/owlapi/fma#FMA_82757 BIOMODELS LOOM
http://stirdf.jst.go.jp/id/200907009204141050 IOBC LOOM