National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Histidine
Synonyms

(S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid

l-Histidine

HISTIDINE

His

Histidine

Definitions

A semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, Histidine is important for maintenance of myelin sheaths that protect nerve cells and is metabolized to the neurotransmitter histamine. Histamines play many roles in immunity, gastric secretion, and sexual functions. Histidine is also required for blood cell manufacture and protects tissues against damage caused by radiation and heavy metals. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29597

ALT_DEFINITION

Amino acid with side chain -CH2-C3H3N2.

CAS_Registry

71-00-1

CHEBI_ID

CHEBI:15971

Chemical_Formula

C6H9N3O2

code

C29597

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CRCH

CTRP

FDA

DEFINITION

A semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, Histidine is important for maintenance of myelin sheaths that protect nerve cells and is metabolized to the neurotransmitter histamine. Histamines play many roles in immunity, gastric secretion, and sexual functions. Histidine is also required for blood cell manufacture and protects tissues against damage caused by radiation and heavy metals. (NCI04)

Display_Name

Histidine

Essential_Amino_Acid

Y

FDA_UNII_Code

4QD397987E

FULL_SYN

(S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid

l-Histidine

HISTIDINE

His

Histidine

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C87704

INFOODS

HISTN_G

label

Histidine

Legacy Concept Name

Histidine

Macronutrient

Y

NSC Number

137773

Nutrient

Y

Preferred_Name

Histidine

prefixIRI

Thesaurus:C29597

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0019602

Unit

g

USDA_ID

512

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68442

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_27570 DRON LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#6162 OCHV LOOM
http://purl.org/sig/ont/fma/fma82755 FMA LOOM
http://localhost/plosthes.2017-1#1655 PLOSTHES LOOM
http://id.nlm.nih.gov/mesh/D006639 MDM LOOM
http://purl.bioontology.org/ontology/MESH/D006639 MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/60260004 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/UPa_UPC00768 UPA LOOM
http://purl.obolibrary.org/obo/SO_0001452 SO LOOM
http://purl.obolibrary.org/obo/SO_0001452 NIFSTD LOOM
http://purl.bioontology.org/ontology/RCD/X807K RCD LOOM
http://www.phoc.org.cn/pmo/class/PMO_00021267 PMAPP-PMO LOOM
http://www.co-ode.org/ontologies/amino-acid/2006/05/18/amino-acid.owl#H AMINO-ACID LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146980 NDFRT LOOM
http://purl.jp/bio/10/gmo/GMO_001170 GMO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003092 LOINC LOOM
http://purl.obolibrary.org/obo/NCIT_C29597 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.142.308 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4018669 VANDF LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Histidine APAONTO LOOM
http://www.co-ode.org/ontologies/galen#Histidine GALEN LOOM
http://www.semanticweb.org/d.rastogi/ontologies/2024/1/altproton#Histidine ALTPROTON LOOM
https://go.drugbank.com/drugs/DB00117 MDM LOOM
http://purl.obolibrary.org/obo/MESH_D006639 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D006639 RH-MESH LOOM
http://purl.jp/bio/4/id/200906013300811877 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/5340 RXNORM LOOM
http://purl.bioontology.org/ontology/CSP/0777-7488 CRISP LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0019602 OCHV LOOM
http://stirdf.jst.go.jp/id/200907042120104149 IOBC LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 FOODON LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 OCMR LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 BIPON LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 CIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 ONSTR LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 ZP LOOM
http://purl.obolibrary.org/obo/CHEBI_27570 OBA LOOM
http://purl.bioontology.org/ontology/SNMI/F-64250 SNMI LOOM
http://purl.obolibrary.org/obo/OMIT_0007798 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.072.329 RH-MESH LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_27570 NPO LOOM
http://purl.org/obo/owlapi/fma#FMA_82755 BIOMODELS LOOM
http://purl.bioontology.org/ontology/LNC/LP15637-9 LOINC LOOM
http://www.cea.fr/ontotoxnuc#Histidine ONTOTOXNUC LOOM
http://www.projecthalo.com/aura#Histidine AURA LOOM