National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Venlafaxine Hydrochloride

Synonyms

Venlafaxine Hydrochloride

VENLAFAXINE HYDROCHLORIDE

Effexor

Definitions

A synthetic ethyl-cyclohexanol derivative used for the treatment of depression, Venlafaxine Hydrochloride is metabolized to O-desmethylvenlafaxine, which potentiates CNS activity. Both venlafaxine and its active metabolite inhibit neuronal reuptake of norepinephrine, dopamine, and serotonin. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29540

CAS_Registry

99300-78-4

CHEBI_ID

CHEBI:9944

Chemical_Formula

C17H27NO2.ClH

code

C29540

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

DEFINITION

A synthetic ethyl-cyclohexanol derivative used for the treatment of depression, Venlafaxine Hydrochloride is metabolized to O-desmethylvenlafaxine, which potentiates CNS activity. Both venlafaxine and its active metabolite inhibit neuronal reuptake of norepinephrine, dopamine, and serotonin. (NCI04)

Display_Name

Venlafaxine Hydrochloride

FDA_UNII_Code

7D7RX5A8MO

FULL_SYN

Venlafaxine Hydrochloride

VENLAFAXINE HYDROCHLORIDE

Effexor

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1278

label

Venlafaxine Hydrochloride

Legacy Concept Name

Venlafaxine_Hydrochloride

Preferred_Name

Venlafaxine Hydrochloride

prefixIRI

Thesaurus:C29540

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0771200

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C265

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