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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Terconazole | |
| Synonyms |
Terconazole TERCONAZOLE Terazol |
|
| Definitions |
A synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and promoting loss of essential intracellular elements. Terconazole is active against Candida sp.. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29493 |
|
| CAS_Registry |
67915-31-5
|
|
| Chemical_Formula |
C26H31Cl2N5O3
|
|
| code |
C29493
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
A synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and promoting loss of essential intracellular elements. Terconazole is active against Candida sp.. (NCI04)
|
|
| FDA_UNII_Code |
0KJ2VE664U
|
|
| FULL_SYN |
Terconazole TERCONAZOLE Terazol
|
|
| label |
Terconazole
|
|
| Legacy Concept Name |
Terconzole
|
|
| NSC Number |
331942
|
|
| Preferred_Name |
Terconazole
|
|
| prefixIRI |
Thesaurus:C29493
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic
|
|
| UMLS_CUI |
C0076115
|
|
| subClassOf |
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