loading...| Preferred Name |
Terbinafine Hydrochloride |
|
| Synonyms |
TERBINAFINE HYDROCHLORIDE Terbinafine Hydrochloride (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine Hydrochloride Lamisil SF 86-327 |
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| Definitions |
A synthetic allylamine derivative structurally related to naftifine, antifungal Terbinafine Hydrochloride blocks ergosterol biosynthesis by inhibition of squalene epoxidase, part of the sterol synthesis pathway for the fungal cell membrane. Highly lipophilic, it tends to accumulate in skin, nails, and fatty tissues. Terbinafine is active against dermatophytes. (NCI04) |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29492 |
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| CAS_Registry |
78628-80-5 |
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| Chemical_Formula |
C21H25N.HCl |
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| code |
C29492 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA |
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| DEFINITION |
A synthetic allylamine derivative structurally related to naftifine, antifungal Terbinafine Hydrochloride blocks ergosterol biosynthesis by inhibition of squalene epoxidase, part of the sterol synthesis pathway for the fungal cell membrane. Highly lipophilic, it tends to accumulate in skin, nails, and fatty tissues. Terbinafine is active against dermatophytes. (NCI04) |
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| FDA_UNII_Code |
012C11ZU6G |
|
| FULL_SYN |
TERBINAFINE HYDROCHLORIDE Terbinafine Hydrochloride (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine Hydrochloride Lamisil SF 86-327 |
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| Has_Free_Acid_Or_Base_Form | ||
| label |
Terbinafine Hydrochloride |
|
| Legacy Concept Name |
Terbinafine_Hydrochloride |
|
| Preferred_Name |
Terbinafine Hydrochloride |
|
| prefixIRI |
Thesaurus:C29492 |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic |
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| UMLS_CUI |
C0771029 |
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| subClassOf |