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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Sertraline Hydrochloride | |
| Synonyms |
SERTRALINE HYDROCHLORIDE Sertraline Hydrochloride Zoloft |
|
| Definitions |
The hydrochloride salt of sertraline, a synthetic derivative of naphthalenamine with anti-serotoninergic and anti-depressant properties. Sertraline appears to selectively inhibit the neuronal uptake of serotonin, raising serotonin levels in the CNS. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29451 |
|
| Accepted_Therapeutic_Use_For |
Major depressive disorder; Obsessive-compulsive disorder; Panic disorder; Posttraumatic stress disorder; Premenstrual dysphoric disorder; Social phobia
|
|
| ALT_DEFINITION |
A drug used to treat depression. It is a type of selective serotonin reuptake inhibitor (SSRI).
|
|
| CAS_Registry |
79559-97-0
|
|
| CHEBI_ID |
CHEBI:9124
|
|
| Chemical_Formula |
C17H17Cl2N.HCl
|
|
| code |
C29451
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA
|
|
| DEFINITION |
The hydrochloride salt of sertraline, a synthetic derivative of naphthalenamine with anti-serotoninergic and anti-depressant properties. Sertraline appears to selectively inhibit the neuronal uptake of serotonin, raising serotonin levels in the CNS.
|
|
| Display_Name |
Sertraline Hydrochloride
|
|
| FDA_UNII_Code |
UTI8907Y6X
|
|
| FULL_SYN |
SERTRALINE HYDROCHLORIDE Sertraline Hydrochloride Zoloft
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Sertraline Hydrochloride
|
|
| Legacy Concept Name |
Sertraline_Hydrochloride
|
|
| NCI_Drug_Dictionary_ID |
322832
|
|
| PDQ_Closed_Trial_Search_ID |
322832
|
|
| PDQ_Open_Trial_Search_ID |
322832
|
|
| Preferred_Name |
Sertraline Hydrochloride
|
|
| prefixIRI |
Thesaurus:C29451
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0600526
|
|
| subClassOf |
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