National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Orlistat
Synonyms

Alli

ORLISTAT

Orlistat

Xenical

Definitions

A reversible active-site inhibitor of gastrointestinal lipases. Orlistat forms a covalent bond with the active serine site in gastric and pancreatic lipases, thereby inhibiting their activity and preventing dietary fat from being hydrolyzed and absorbed. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29303

CAS_Registry

96829-58-2

Chemical_Formula

C29H53NO5

code

C29303

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A reversible active-site inhibitor of gastrointestinal lipases. Orlistat forms a covalent bond with the active serine site in gastric and pancreatic lipases, thereby inhibiting their activity and preventing dietary fat from being hydrolyzed and absorbed. (NCI04)

FDA_UNII_Code

95M8R751W8

FULL_SYN

Alli

ORLISTAT

Orlistat

Xenical

label

Orlistat

Legacy Concept Name

Orlistat

Preferred_Name

Orlistat

prefixIRI

Thesaurus:C29303

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0076275

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29715

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Delete Mapping To Ontology Source
http://purl.jp/bio/4/id/200906084788357600 IOBC LOOM
http://purl.obolibrary.org/obo/NCIT_C29303 BERO LOOM
http://purl.bioontology.org/ontology/RCD/aw1.. RCD LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0076275 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14929 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/D000077403 MESH LOOM
https://go.drugbank.com/drugs/DB01083 MDM LOOM
http://purl.obolibrary.org/obo/CHEBI_94686 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_94686 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_94686 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_94686 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_94686 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_94686 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_94686 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_94686 DRON LOOM
http://www.drugbank.ca/drugs/DB01083 FTC LOOM
http://www.co-ode.org/ontologies/galen#Orlistat GALEN LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClassb9aae49d_7854_4535_b4fa_45f25c04ef88 WWECA LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387007000 SNOMEDCT LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass484f196b_4a70_403c_95a1_6d1fac9ca3ff WWECA LOOM
http://stirdf.jst.go.jp/id/200907054848973036 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148610 NDFRT LOOM
http://purl.bioontology.org/ontology/RXNORM/37925 RXNORM LOOM
http://purl.bioontology.org/ontology/ATC/A08AB01 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C055122 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4021159 VANDF LOOM
http://purl.obolibrary.org/obo/dinto_DB01083 DINTO LOOM