National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Nitrofurantoin
Synonyms

NITROFURANTOIN

Nitrofurantoin

Macrodantin

Macrobid

Definitions

A synthetic derivative of imidazolidinedione, Nitrofurantoin inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoin is used prophylactically as a urinary anti-infective agent against most gram-positive and gram-negative organisms and for long-term suppression of infections. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29293

CAS_Registry

67-20-9

CHEBI_ID

CHEBI:71415

Chemical_Formula

C8H6N4O5

code

C29293

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic derivative of imidazolidinedione, Nitrofurantoin inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoin is used prophylactically as a urinary anti-infective agent against most gram-positive and gram-negative organisms and for long-term suppression of infections. (NCI04)

FDA_UNII_Code

927AH8112L

FULL_SYN

NITROFURANTOIN

Nitrofurantoin

Macrodantin

Macrobid

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66241

label

Nitrofurantoin

Legacy Concept Name

Nitrofurantoin

NSC Number

2107

44150

Preferred_Name

Nitrofurantoin

prefixIRI

Thesaurus:C29293

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0028156

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C255

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http://purl.bioontology.org/ontology/MESH/D009582 MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_7591 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_7591 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_7591 ODNAE LOOM
http://purl.bioontology.org/ontology/LNC/LP16140-3 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.640.600.566 RH-MESH LOOM
http://purl.obolibrary.org/obo/OMIT_0010602 OMIT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373543005 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU008460 LOINC LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147151 ODAE LOOM
http://purl.obolibrary.org/obo/XCO_0001198 XCO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D009582 RH-MESH LOOM
http://purl.jp/bio/4/id/200906091933051821 IOBC LOOM
http://purl.bioontology.org/ontology/RCD/eg1.. RCD LOOM
http://purl.obolibrary.org/obo/ARO_0000075 ARO LOOM
http://stirdf.jst.go.jp/id/200907098606283636 IOBC LOOM
rgo:15161 GAMUTS LOOM
http://purl.bioontology.org/ontology/ATC/J01XE01 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0028156 OCHV LOOM
http://purl.bioontology.org/ontology/SNMI/C-55620 SNMI LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147151 NDFRT LOOM
http://www.co-ode.org/ontologies/galen#Nitrofurantoin GALEN LOOM
http://purl.bioontology.org/ontology/VANDF/4018849 VANDF LOOM
http://purl.obolibrary.org/obo/NCIT_C29293 BERO LOOM
http://purl.bioontology.org/ontology/RXNORM/7454 RXNORM LOOM
http://purl.obolibrary.org/obo/MESH_D009582 BERO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017217 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_71415 OBA LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Nitrofurantoin STMSO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8738 OCHV LOOM
https://go.drugbank.com/drugs/DB00698 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.312.649.566 RH-MESH LOOM