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National Cancer Institute Thesaurus
| Preferred Name | Metoprolol Tartrate | |
| Synonyms |
Metoprolol Tartrate METOPROLOL TARTRATE Lopressor |
|
| Definitions |
The tartrate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol tartrate antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction, and consequently a diminished cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thus decreasing sympathetic activation, including vasoconstriction, aldosterone secretion. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29255 |
|
| CAS_Registry |
56392-17-7
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|
| Chemical_Formula |
2C15H25NO3.C4H6O6
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|
| code |
C29255
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|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
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| Contributing_Source |
CTRP FDA
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|
| DEFINITION |
The tartrate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol tartrate antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction, and consequently a diminished cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thus decreasing sympathetic activation, including vasoconstriction, aldosterone secretion.
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|
| Display_Name |
Metoprolol Tartrate
|
|
| FDA_UNII_Code |
W5S57Y3A5L
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|
| FULL_SYN |
Metoprolol Tartrate METOPROLOL TARTRATE Lopressor
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| Has_Free_Acid_Or_Base_Form | ||
| label |
Metoprolol Tartrate
|
|
| Legacy Concept Name |
Metoprolol_Tartrate
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|
| NCI_Drug_Dictionary_ID |
809246
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| Preferred_Name |
Metoprolol Tartrate
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|
| prefixIRI |
Thesaurus:C29255
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| Semantic_Type |
Organic Chemical Pharmacologic Substance
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| UMLS_CUI |
C0700548
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| subClassOf |
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