loading...| Preferred Name |
Loratadine |
|
| Synonyms |
1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-, Ethyl Ester Claritin LORATADINE Loratadine |
|
| Definitions |
A piperidine histamine H1-receptor antagonist with anti-allergic properties and without sedative effects. Loratadine blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. Loratadine does not cross the blood-brain barrier and does not cause central nervous system effects. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29162 |
|
| CAS_Registry |
79794-75-5 |
|
| Chemical_Formula |
C22H23ClN2O2 |
|
| code |
C29162 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A piperidine histamine H1-receptor antagonist with anti-allergic properties and without sedative effects. Loratadine blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. Loratadine does not cross the blood-brain barrier and does not cause central nervous system effects. |
|
| FDA_UNII_Code |
7AJO3BO7QN |
|
| FULL_SYN |
1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-, Ethyl Ester Claritin LORATADINE Loratadine |
|
| label |
Loratadine |
|
| Legacy Concept Name |
Loratadine |
|
| NSC Number |
721075 |
|
| Preferred_Name |
Loratadine |
|
| prefixIRI |
Thesaurus:C29162 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0065180 |
|
| subClassOf |