National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Fluorometholone

Synonyms

Fluorometholone

FLUOROMETHOLONE

Fluor-Op

Oxylone

Definitions

A synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Fluorometholone exerts its effects by interacting with cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29058

CAS_Registry

426-13-1

CHEBI_ID

CHEBI:31625

Chemical_Formula

C22H29FO4

code

C29058

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Fluorometholone exerts its effects by interacting with cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

FDA_UNII_Code

SV0CSG527L

FULL_SYN

Fluorometholone

FLUOROMETHOLONE

Fluor-Op

Oxylone

label

Fluorometholone

Legacy Concept Name

Fluorometholone

NSC Number

33001

Preferred_Name

Fluorometholone

prefixIRI

Thesaurus:C29058

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0016351

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C521

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http://purl.obolibrary.org/obo/CHEBI_31625 CHEBI LOOM
https://go.drugbank.com/drugs/DB00324 MDM LOOM
http://purl.bioontology.org/ontology/MESH/D005469 MESH LOOM
http://purl.bioontology.org/ontology/ATC/D07AB06 ATC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146545 NDFRT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/2925007 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/ATC/S01BA07 ATC LOOM
http://purl.obolibrary.org/obo/NCIT_C29058 BERO LOOM
http://purl.jp/bio/4/id/200906025326440395 IOBC LOOM
http://stirdf.jst.go.jp/id/200907062132421361 IOBC LOOM
http://purl.obolibrary.org/obo/dinto_DB00324 DINTO LOOM
http://purl.bioontology.org/ontology/LNC/LP35870-2 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#5126 OCHV LOOM
http://www.co-ode.org/ontologies/galen#Fluorometholone GALEN LOOM
http://purl.bioontology.org/ontology/RXNORM/4491 RXNORM LOOM
http://purl.bioontology.org/ontology/NDDF/002194 NDDF LOOM
http://purl.bioontology.org/ontology/ATC/D10AA01 ATC LOOM
http://www.drugbank.ca/drugs/DB00324 FTC LOOM
http://purl.bioontology.org/ontology/SNMI/C-97050 SNMI LOOM
http://purl.bioontology.org/ontology/ATC/C05AA06 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.745.432.719.349 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018684 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/OMIT_0006678 OMIT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU018757 LOINC LOOM
http://purl.obolibrary.org/obo/CHEBI_31625 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_31625 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_31625 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_31625 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_31625 NIFSTD LOOM
http://purl.bioontology.org/ontology/RCD/k65.. RCD LOOM
http://purl.bioontology.org/ontology/ATC/S01CB05 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0016351 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4018212 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.908.431 RH-MESH LOOM
http://purl.obolibrary.org/obo/MESH_D005469 BERO LOOM
https://github.com/sap218/ocimido/blob/master/ontology/ocimido.owl#OCIMIDO_00195 OCIMIDO LOOM
http://purl.bioontology.org/ontology/ATC/D07XB04 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D005469 RH-MESH LOOM