National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Diphenoxylate Hydrochloride
Synonyms

DIPHENOXYLATE HYDROCHLORIDE

Diphenoxylate Hydrochloride

Definitions

The hydrochloride salt form of diphenoxylate, a piperidine derivate, chemically related to narcotic meperidine, with antidiarrheal activity and devoid of central nervous system (CNS) activity. Diphenoxylate acts on opioid receptors in the gastrointestinal tract, thereby decreasing gastrointestinal motility and causing constipation or preventing diarrhea.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28995

CAS_Registry

3810-80-8

CHEBI_ID

CHEBI:59784

Chemical_Formula

C30H32N2O2.HCl

code

C28995

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt form of diphenoxylate, a piperidine derivate, chemically related to narcotic meperidine, with antidiarrheal activity and devoid of central nervous system (CNS) activity. Diphenoxylate acts on opioid receptors in the gastrointestinal tract, thereby decreasing gastrointestinal motility and causing constipation or preventing diarrhea.

FDA_UNII_Code

W24OD7YW48

FULL_SYN

DIPHENOXYLATE HYDROCHLORIDE

Diphenoxylate Hydrochloride

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62024

label

Diphenoxylate Hydrochloride

Legacy Concept Name

Diphenoxylate

Preferred_Name

Diphenoxylate Hydrochloride

prefixIRI

Thesaurus:C28995

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0282145

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C266

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