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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Dimenhydrinate | |
| Synonyms |
Dimenhydrinate DIMENHYDRINATE Dramamine |
|
| Definitions |
An ethanolamine and first-generation histamine antagonist with anti-allergic activity. Dimenhydrinate competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, GI smooth muscle spasm. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28992 |
|
| CAS_Registry |
523-87-5
|
|
| CHEBI_ID |
CHEBI:4604
|
|
| Chemical_Formula |
C17H21NO.C7H7ClN4O2
|
|
| code |
C28992
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
An ethanolamine and first-generation histamine antagonist with anti-allergic activity. Dimenhydrinate competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, GI smooth muscle spasm.
|
|
| FDA_UNII_Code |
JB937PER5C
|
|
| FULL_SYN |
Dimenhydrinate DIMENHYDRINATE Dramamine
|
|
| label |
Dimenhydrinate
|
|
| Legacy Concept Name |
Dimenhydrinate
|
|
| NSC Number |
117855
|
|
| Preferred_Name |
Dimenhydrinate
|
|
| prefixIRI |
Thesaurus:C28992
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0012381
|
|
| subClassOf |
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