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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Benzocaine | |
| Synonyms |
Baby Anbesol Chloraseptic Ethyl 4-aminobenzoate Ethyl P-Aminobenzoate Anesthesin BENZOCAINE Benzocaine Norcain Norcaine Ora-Jel |
|
| Definitions |
An ester of paraaminobenzoic acid, lacking the terminal diethylamino group of procaine, with anesthetic activity. Benzocaine binds to the sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited, thereby blocking the initiation and conduction of nerve impulses. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28923 |
|
| CAS_Registry |
94-09-7
|
|
| CHEBI_ID |
CHEBI:116735
|
|
| Chemical_Formula |
C9H11NO2
|
|
| code |
C28923
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
An ester of paraaminobenzoic acid, lacking the terminal diethylamino group of procaine, with anesthetic activity. Benzocaine binds to the sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited, thereby blocking the initiation and conduction of nerve impulses.
|
|
| FDA_UNII_Code |
U3RSY48JW5
|
|
| FULL_SYN |
Baby Anbesol Chloraseptic Ethyl 4-aminobenzoate Ethyl P-Aminobenzoate Anesthesin BENZOCAINE Benzocaine Norcain Norcaine Ora-Jel
|
|
| Has_Salt_Form | ||
| label |
Benzocaine
|
|
| Legacy Concept Name |
Benzocaines
|
|
| NSC Number |
41531
|
|
| Preferred_Name |
Benzocaine
|
|
| prefixIRI |
Thesaurus:C28923
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0005059
|
|
| subClassOf |
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