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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Caspofungin | |
| Synonyms |
Caspofungin CASPOFUNGIN |
|
| Definitions |
An antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. Caspofungin inhibits 1,3-beta-glucan synthase, resulting in decreased synthesis of beta(1,3)-D-glucan (an essential component of the fungal cell wall), weakening of the fungal cell wall, and fungal cell wall rupture. This agent is active against Aspergillus and Candida species. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28910 |
|
| CAS_Registry |
162808-62-0
|
|
| CHEBI_ID |
CHEBI:474180
|
|
| Chemical_Formula |
C52H88N10O15
|
|
| code |
C28910
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA HemOnc
|
|
| DEFINITION |
An antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. Caspofungin inhibits 1,3-beta-glucan synthase, resulting in decreased synthesis of beta(1,3)-D-glucan (an essential component of the fungal cell wall), weakening of the fungal cell wall, and fungal cell wall rupture. This agent is active against Aspergillus and Candida species.
|
|
| FDA_UNII_Code |
F0XDI6ZL63
|
|
| FULL_SYN |
Caspofungin CASPOFUNGIN
|
|
| Has_Salt_Form | ||
| label |
Caspofungin
|
|
| Legacy Concept Name |
Caspofungin
|
|
| Preferred_Name |
Caspofungin
|
|
| prefixIRI |
Thesaurus:C28910
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic
|
|
| UMLS_CUI |
C0537894
|
|
| subClassOf |
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