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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Anthralin | |
| Synonyms |
1,8-Dihydroxy-9(10H)-anthracenone ANTHRALIN Anthralin |
|
| Definitions |
A natural anthraquinone derivative, anti-psoriatic and anti-inflammatory Anthralin (dithranol) controls skin growth by reducing DNA synthesis and mitotic activity in the hyperplastic epidermis, restoring a normal rate of cell proliferation and keratinization. Used topically in the treatment of psoriasis, dermatoses, and alopecia areata, it is also used in biomedical research due to its effect on EGFR autophosphorylation. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28827 |
|
| CAS_Registry |
1143-38-0 480-22-8
|
|
| CHEBI_ID |
CHEBI:37510 CHEBI:2756
|
|
| Chemical_Formula |
C14H10O3
|
|
| code |
C28827
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
A natural anthraquinone derivative, anti-psoriatic and anti-inflammatory Anthralin (dithranol) controls skin growth by reducing DNA synthesis and mitotic activity in the hyperplastic epidermis, restoring a normal rate of cell proliferation and keratinization. Used topically in the treatment of psoriasis, dermatoses, and alopecia areata, it is also used in biomedical research due to its effect on EGFR autophosphorylation. (NCI04)
|
|
| FDA_UNII_Code |
U8CJK0JH5M
|
|
| FULL_SYN |
1,8-Dihydroxy-9(10H)-anthracenone ANTHRALIN Anthralin
|
|
| label |
Anthralin
|
|
| Legacy Concept Name |
Anthralin
|
|
| NSC Number |
43970 629313
|
|
| Preferred_Name |
Anthralin
|
|
| prefixIRI |
Thesaurus:C28827
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0003166
|
|
| subClassOf |
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