National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Acebutolol Hydrochloride

Synonyms

Acebutolol Hydrochloride

ACEBUTOLOL HYDROCHLORIDE

Definitions

The hydrochloride salt form of acebutolol, a synthetic butyranilide derivative with hypotensive and antiarrhythmic activity. Acebutolol acts as a cardioselective beta-adrenergic antagonist with little effect on bronchial receptors and has intrinsic sympathomimetic properties. Having stabilizing and quinidine-like effects on cardiac rhythm, Acebutolol is used in ventricular arrhythmias. Other indications include hypertension, alone or in combinations with other agents. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28806

CAS_Registry

34381-68-5

CHEBI_ID

CHEBI:2380

Chemical_Formula

C18H28N2O4.ClH

code

C28806

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt form of acebutolol, a synthetic butyranilide derivative with hypotensive and antiarrhythmic activity. Acebutolol acts as a cardioselective beta-adrenergic antagonist with little effect on bronchial receptors and has intrinsic sympathomimetic properties. Having stabilizing and quinidine-like effects on cardiac rhythm, Acebutolol is used in ventricular arrhythmias. Other indications include hypertension, alone or in combinations with other agents. (NCI04)

FDA_UNII_Code

B025Y34C54

FULL_SYN

Acebutolol Hydrochloride

ACEBUTOLOL HYDROCHLORIDE

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61525

label

Acebutolol Hydrochloride

Legacy Concept Name

Acebutolol

Preferred_Name

Acebutolol Hydrochloride

prefixIRI

Thesaurus:C28806

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0543447

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29576

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