National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Camptothecin Analogue
Synonyms

camptothecin analogue

Camptothecin Analog

Camptothecin Analogue

Definitions

Any substance based on the structure of camptothecin that stabilizes topoisomerase I-DNA covalent complexes, thereby causing DNA damage and apoptosis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2843

ALT_DEFINITION

An anticancer drug related in structure to camptothecin, a topoisomerase inhibitor. One such drug is aminocamptothecin.

code

C2843

DEFINITION

Any substance based on the structure of camptothecin that stabilizes topoisomerase I-DNA covalent complexes, thereby causing DNA damage and apoptosis.

FULL_SYN

camptothecin analogue

Camptothecin Analog

Camptothecin Analogue

label

Camptothecin Analogue

Legacy Concept Name

Camptothecin_Analogue

Preferred_Name

Camptothecin Analogue

prefixIRI

Thesaurus:C2843

Semantic_Type

Chemical Viewed Structurally

UMLS_CUI

C1516155

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1904

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