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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Modafinil | |
| Synonyms |
MODAFINIL Modafinil Provigil modafinil |
|
| Definitions |
A synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26661 |
|
| Accepted_Therapeutic_Use_For |
Narcolepsy
|
|
| ALT_DEFINITION |
A drug that is being studied as a treatment for fatigue in patients with cancer. It belongs to the family of drugs called stimulants.
|
|
| CAS_Registry |
68693-11-8
|
|
| Chemical_Formula |
C15H15NO2S
|
|
| code |
C26661
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA
|
|
| DEFINITION |
A synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. (NCI04)
|
|
| Display_Name |
Modafinil
|
|
| FDA_UNII_Code |
R3UK8X3U3D
|
|
| FULL_SYN |
MODAFINIL Modafinil Provigil modafinil
|
|
| label |
Modafinil
|
|
| Legacy Concept Name |
Modafinil
|
|
| NCI_Drug_Dictionary_ID |
256449
|
|
| PDQ_Closed_Trial_Search_ID |
256449
|
|
| PDQ_Open_Trial_Search_ID |
256449
|
|
| Preferred_Name |
Modafinil
|
|
| prefixIRI |
Thesaurus:C26661
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0066677
|
|
| subClassOf |
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